๐Ÿงฌ Basics of Genetic Analysis

๐Ÿ“… Friday, July 25, 2025 | ๐Ÿ•— 8:00 am โ€“ 12:00 pm
๐Ÿ“ Westin Harbour Castle โ€“ Pier 2, Toronto, Canada
๐Ÿ‘ฅ In-person attendance only


๐ŸŽฏ Summary and Setup

This immersive ISTAART workshop provides an introduction to the fundamentals of genetic analysis within brain imaging genetics research. It combines theoretical concepts with hands-on practical sessions to give attendees a solid foundation.


๐Ÿ’ป Connecting to Your Virtual Machine

Participants will access a cloud-hosted Linux-based VM with pre-installed tools. You should have received two emails from no-reply@accounts.eu-west-2.amazonappstream.com.

๐Ÿšซ If you havenโ€™t received the email, contact a facilitator.


๐Ÿ—“๏ธ Agenda

Time Session Speaker(s)
8:00 am Welcome / Intro Tavia Evans
8:10 am How to design your genetics experiment Natalia Vilor-Tejedor
8:20 am How to get data, QC, and imputation Natalia Vilor-Tejedor
9:00 am SNP analysis Yuetiva Robles
9:40 am Break ย 
9:50 am Genome Wide Association Studies (GWAS) Yuetiva Robles
10:40 am Polygenic Risk Score (PRS) calculation with PRSice Emma Luckett
11:35 am PostGWAS analysis: Understanding biological pathways Krishna Rani Kalari, Karunya Kandimalla
11:55 am End / Review Tavia Evans, Natalia Vilor-Tejedor, Junhao Wen

๐ŸŽ“ Learning Objectives

  1. Perform basic genetic analyses (SNPs, GWAS, PRS).
  2. Understand and compare different genetic techniques.
  3. Interpret outputs in the context of imaging genetics.

๐Ÿ“‹ Requirements


๐Ÿ”— Webinars & Slides

Webinar Topic Slides
Design your genetics experiment Slides Intro
QC and Imputation Slides QC Imputation, Pipeline QC, Pipeline Imputation
Single SNP association analysis Slides SNP association
Genome Wide Association Studies Slides GWAS
Polygenic Risk Scores Slides PRS
PostGWAS analysis Slides postGWAS

๐Ÿ‘ฅ Organizing Committee

Speakers

Teaching Aids


This workshop is supported by: Alzheimerโ€™s Association, ISTAART Neuroimaging PIA - Working group Brain Imaging Genetics

Special thanks to ADNI datasets, and infrastructure support from UCL team.

Interested in learning more? Check out our recent book chapter: Vilor-Tejedor, N. et al. (2025). Genomics and Transcriptomics of Alzheimer Disease. In: Tarawneh, R. (eds) Biomarkers of Neurodegenerative Disorders. Springer, Cham. https://doi.org/10.1007/978-3-031-80849-4_13.

ยฉ 2025 AAIC Workshop Basics of Genetics โ€ข Maintained by @GeneticNeuroStats
Hosted on GitHub Pages